Project
In this project we were tasked with choosing a disease that is caused by a protein in the body and reseach it to figure out why this happends. Me and my group decided on ALS and started our research. We discovered that it is caused by the protein SOD1 being mis-folded during protein synthesis.
Protein SynthesisA strand of DNA splits in order to let the mRNA connect to the split DNA to perform transcription in the nucleus. The mRNA disconnects and travels to the ribosome where
tRNA carrying an amino acid connects to the mRNA in the ribosome releasing the amino acids to form polypeptide chains. The polypeptide chains changes structure to become α helix and β sheets. These combine to form domains when all of the domains are combined, they form a protein. |
Poster
Content
Protein mis-folding: This is when there is an error in the code that causes the folding to be misshapen and incorrect.
DNA: the base of life. Made up of amino acids and are the orders towards the organelles in the cells.
Translation: This is the step where the anti-codons connect to the base pairs and produce the polypeptide chain from the amino acids.
mRNA: the genetic code copy that is used to go to other parts of the cell.
Codon: the three sections in the genetic code that the ribosome reads in.
Anti-codon: the part that attaches to the code according to the base pairs.
Transcription: This is the step where the DNA is copied from the mRNA, which is released into the cell to other organelles.
Ribosome: the organelle responsible for making the polypeptide chains.
Amino acid: used to create proteins
tRNA: the RNA that is responsible for transferring, acting as messenger. This is crucial to making proteins.
Folding: the step where the Alpha helix's and the Beta sheets fold to create a protein.
Protein: The macromolecule used to
ALS: A nervous system disease that weakens muscles and impacts physical function.
DNA: the base of life. Made up of amino acids and are the orders towards the organelles in the cells.
Translation: This is the step where the anti-codons connect to the base pairs and produce the polypeptide chain from the amino acids.
mRNA: the genetic code copy that is used to go to other parts of the cell.
Codon: the three sections in the genetic code that the ribosome reads in.
Anti-codon: the part that attaches to the code according to the base pairs.
Transcription: This is the step where the DNA is copied from the mRNA, which is released into the cell to other organelles.
Ribosome: the organelle responsible for making the polypeptide chains.
Amino acid: used to create proteins
tRNA: the RNA that is responsible for transferring, acting as messenger. This is crucial to making proteins.
Folding: the step where the Alpha helix's and the Beta sheets fold to create a protein.
Protein: The macromolecule used to
ALS: A nervous system disease that weakens muscles and impacts physical function.
Reflections
This project was fun and it was interesting to learn about how protein synthesis even though it took a while to understand. Me and my group got along well and it was easy to express anything that needed to be said. My high was getting done with the research and being able to put all that we learned down onto paper. My low was felling like we were done and then realising that we hadn't found the code for our DNA, mRNA, and polypeptide chain. We worked well together but we didn't have the best work ethic as a group.